AILERON Therapeutics is a biopharmaceutical company developing a breakthrough class of drugs called Stapled Peptides. This new class of drugs represents the first general solution for modulating intracellular protein-protein interactions, which have been identified as critical control points for most human diseases. Aileron's new therapeutic modality creates a unique opportunity to exploit potentially thousands of currently "undruggable" targets with applications in all human diseases.

Stapled Peptide Targets

Stapled Peptides target intracellular control points that cannot be modulated by current therapeutics.

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“Stapling” Peptides

Stapled Peptides are produced by connecting two structurally optimized amino acids.

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Recent Publications

In an article published in Nature, Aileron’s proprietary Stapled Peptide drug candidate was shown to target a new and fundamental therapeutic mechanism.

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Update: Aileron Therapeutics Closes $40M Financing To Advance Stapled Peptide Platform   Press Release